Magnetic Resonance techniques powerful tools for antioxidant activity investigation in supramolecular assemblies

The advantage of the magnetic resonance methods is the ability to give information about processes at the atomic level selecting out, of total magnetic susceptibility, the particular contribution of interest. Both Nuclear Magnetic Resonance (NMR) and Electron Paramagnetic Resonance (EPR) are non-destructive analytical tool that enables to investigate molecular structure, measure relative and absolute concentrations and intermolecular interactions occurring among active compounds. This work was aimed at explore the antiradical activity of some antioxidant, like oleuropein, tyrosol and hydroxytyrosol,1 both in solution and in emulsion by the ability of them to quench the Fremy’s salt (potassium nitrosodisulfonate). In fact, EPR technique is very suitable for describing and measure the radical-scavenging processes2 and NMR spectroscopy is one of the most convenient methods for simultaneous monitoring of changes in aggregate morphologies of interaction between components.