An 8.5-year-old, neutered female ferret (Mustela putorius furo) was presented with tachypnoea, polyuria, polydipsia, anorexia and depression. Radiographs revealed multiple osteolytic lesions of the bone, characterized cytologically by the infiltration of medium- to large-sized lymphocytes. The animal was humanely destroyed and post-mortem examination revealed multifocal masses obliterating the bone marrow of the mandible, right and left humeri and femur, and consisting of an infiltrative population of neoplastic lymphocytes. Immunohistochemical labelling for CD3 and CD79a revealed a CD3-positive neoplastic population. A diagnosis of polyostotic T-cell lymphoma was made, which is the first report of this condition in a ferret.
Polyostotic Lymphoma in a Ferret (Mustela putorius furo)
PALMIERI, CHIARA
2016-01-01
Abstract
An 8.5-year-old, neutered female ferret (Mustela putorius furo) was presented with tachypnoea, polyuria, polydipsia, anorexia and depression. Radiographs revealed multiple osteolytic lesions of the bone, characterized cytologically by the infiltration of medium- to large-sized lymphocytes. The animal was humanely destroyed and post-mortem examination revealed multifocal masses obliterating the bone marrow of the mandible, right and left humeri and femur, and consisting of an infiltrative population of neoplastic lymphocytes. Immunohistochemical labelling for CD3 and CD79a revealed a CD3-positive neoplastic population. A diagnosis of polyostotic T-cell lymphoma was made, which is the first report of this condition in a ferret.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
