Research highlights:Domoic acid (DA)-induced glutamate excitotoxicity may cause astrocytic damage. Damaged astrocytes may release arginine, with subsequent arginine uptake by eosinophils. An increased turnover and proliferation rate of eosinophils could subsequently occur. The enteric nervous system from DA-intoxicated animals should be properly investigated.[...]
Eosinophilia and domoic acid exposure: A pathogenetic hypothesis
DI GUARDO, Giovanni
2011-01-01
Abstract
Research highlights:Domoic acid (DA)-induced glutamate excitotoxicity may cause astrocytic damage. Damaged astrocytes may release arginine, with subsequent arginine uptake by eosinophils. An increased turnover and proliferation rate of eosinophils could subsequently occur. The enteric nervous system from DA-intoxicated animals should be properly investigated.[...]File in questo prodotto:
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