The palladium-catalyzed arylation of the α-methylene-γ-butyrolactone proceeds in good yields and may be directed toward the synthesis of 3-benzylfuran-2(5H)-ones when the starting aryl iodides contain strongly electron-withdrawing groups. The combined palladium-catalyzed arylation/hydrogenation of the α-methylene-γ-butyrolactone represents a new simple entry into functionalized α-benzyl-γ-butyrolactones.

Palladium-Catalyzed Arylation of alfa-Methylene-gamma-butyrolactone: 3-Benzylfuran-2(5H)-ones vs (Z)-Benzylidene-gamma-butyrolactones and Their Reduction to 3-Benzyl-gamma-butyrolactones

CHIARINI, MARCO;
2000

Abstract

The palladium-catalyzed arylation of the α-methylene-γ-butyrolactone proceeds in good yields and may be directed toward the synthesis of 3-benzylfuran-2(5H)-ones when the starting aryl iodides contain strongly electron-withdrawing groups. The combined palladium-catalyzed arylation/hydrogenation of the α-methylene-γ-butyrolactone represents a new simple entry into functionalized α-benzyl-γ-butyrolactones.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11575/6604
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