Feline immunodeficiency virus (FIV) infection in cats is regarded as a highly valuable model for HIV infection's pathogenesis. In this respect, it is becoming increasingly clear that HIV infection's progression and outcome tend to be different in Th1-dominant as compared to Th2-dominant patients. The same could be also true for FIV-infected cats, so that it would be worth investigating whether a more or less “pronounced” resistance to FIV colonization and replication may exist between Th1 and Th2 lymphocytes in relation to the dominant T-cell immunophenotype of TRIMCyp-transgenic cats.[...]
Cat transgenesis and feline versus human AIDS
DI GUARDO, Giovanni
2012-01-01
Abstract
Feline immunodeficiency virus (FIV) infection in cats is regarded as a highly valuable model for HIV infection's pathogenesis. In this respect, it is becoming increasingly clear that HIV infection's progression and outcome tend to be different in Th1-dominant as compared to Th2-dominant patients. The same could be also true for FIV-infected cats, so that it would be worth investigating whether a more or less “pronounced” resistance to FIV colonization and replication may exist between Th1 and Th2 lymphocytes in relation to the dominant T-cell immunophenotype of TRIMCyp-transgenic cats.[...]File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
