Antimicrobial peptides (AMPs) are natural components of the innate immune system that act through physical disruption of bacterial membranes, offering a promising alternative to traditional antibiotics. No prior data existed on the use of AMP-based medical devices in dogs and cats. This pilot study aimed to evaluate the efficacy of an AMPS patch for open wounds, focusing on granulation tissue formation, local infection control, and reduction of systemic antibiotic use.

Use of stabilized antimicrobial peptides for treatment of open wounds in dogs and cats: A pilot study

Umberto Maggiolini
;
Amanda Bianchi;Andrea Paolini;Francesco Collivignarelli;Roberto Tamburro
2026-01-01

Abstract

Antimicrobial peptides (AMPs) are natural components of the innate immune system that act through physical disruption of bacterial membranes, offering a promising alternative to traditional antibiotics. No prior data existed on the use of AMP-based medical devices in dogs and cats. This pilot study aimed to evaluate the efficacy of an AMPS patch for open wounds, focusing on granulation tissue formation, local infection control, and reduction of systemic antibiotic use.
2026
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11575/181524
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