Guanosine possesses the intrinsic ability to self-assemble in aqueous environments, giving rise to supramolecular architectures ranging from G-quartets to G-quadruplexes. These, in turn, can undergo cross-linking or entanglement, forming a molecular hydrogel with promising biotechnological properties. Infrared spectroscopy can successfully unravel the structural and dynamic properties of these supramolecular assemblies, revealing spectral features indicative of quartets, octamers, and quadruplex formation, and is used to monitor the formation of G-hydrogels.
Unveiling guanosine hydrogel properties: Mid and Far infrared spectroscopic insights
Notarstefano V.
;
2025-01-01
Abstract
Guanosine possesses the intrinsic ability to self-assemble in aqueous environments, giving rise to supramolecular architectures ranging from G-quartets to G-quadruplexes. These, in turn, can undergo cross-linking or entanglement, forming a molecular hydrogel with promising biotechnological properties. Infrared spectroscopy can successfully unravel the structural and dynamic properties of these supramolecular assemblies, revealing spectral features indicative of quartets, octamers, and quadruplex formation, and is used to monitor the formation of G-hydrogels.File in questo prodotto:
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