This study provides a description of the surveillance strategies adopted during an outbreak caused by the ST79 genotype of Coxiella burnetii, which has been endemic in the area for over a decade. It provides a detailed overview of C. burnetii infection in both wild and domestic animal populations in the Abruzzo and Molise regions. In the review of C. burnetii infections, data on the prevalence and impact of the bacterium in different animal hosts have been presented. This includes molecular findings that allow an assessment of the dynamics of infection before and after vaccination. In addition, this study proposes a novel NGS-based approach for in silico multi-spacer typing (MST) of C. burnetii. The results highlight the importance of surveillance and control measures in domestic animal populations to reduce the risk of zoonotic transmission.
Coxiella burnetii: A Brief Summary of the Last Five Years of Its Presence in the Abruzzo and Molise Regions in Italy
Lomellini L.;Coccaro A.;Cantelmi M. C.;Merola C.;Di Teodoro G.;
2024-01-01
Abstract
This study provides a description of the surveillance strategies adopted during an outbreak caused by the ST79 genotype of Coxiella burnetii, which has been endemic in the area for over a decade. It provides a detailed overview of C. burnetii infection in both wild and domestic animal populations in the Abruzzo and Molise regions. In the review of C. burnetii infections, data on the prevalence and impact of the bacterium in different animal hosts have been presented. This includes molecular findings that allow an assessment of the dynamics of infection before and after vaccination. In addition, this study proposes a novel NGS-based approach for in silico multi-spacer typing (MST) of C. burnetii. The results highlight the importance of surveillance and control measures in domestic animal populations to reduce the risk of zoonotic transmission.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
