Spontaneous ocular squamous cell carcinoma in two twin goats: Morphopathological and aetiological investigations

Mara', M.; GUARDO G, DI .; Venuti, A.; Marruchella, G.; Palmieri, C; RUGERIIS M, DE .; Petrizzi, L.; Simeone, P.; Rizzo, C.; DELLA SALDA, L.

doi:10.1016/j.jcpa.2004.06.007

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Ocular squamous cell carcinoma (OSCC) is a well-characterized tumour occurring spontaneously in cattle and other mammalian species but not previously reported in the goat. This report describes the histological features of well-differentiated OSCCs in twin goats. Biomolecular investigations led to the identification of Papillomavirus-related DNA sequences within the neoplastic ocular parenchyma of both animals, but immunohistochemical and ultrastructural studies failed to demonstrate viral particles. A putative role of Papillomavirus in the aetiology of OSCC is discussed, together with other possible causative factors.[...]

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11575/13275

Titolo:	Spontaneous ocular squamous cell carcinoma in two twin goats: Morphopathological and aetiological investigations
Autori interni:	DI GUARDO, Giovanni MARRUCHELLA, GIUSEPPE PALMIERI, CHIARA PETRIZZI, Lucio DELLA SALDA, Leonardo
Data di pubblicazione:	2005
Rivista:	JOURNAL OF COMPARATIVE PATHOLOGY
Abstract:	Ocular squamous cell carcinoma (OSCC) is a well-characterized tumour occurring spontaneously in cattle and other mammalian species but not previously reported in the goat. This report describes the histological features of well-differentiated OSCCs in twin goats. Biomolecular investigations led to the identification of Papillomavirus-related DNA sequences within the neoplastic ocular parenchyma of both animals, but immunohistochemical and ultrastructural studies failed to demonstrate viral particles. A putative role of Papillomavirus in the aetiology of OSCC is discussed, together with other possible causative factors.[...]
Handle:	http://hdl.handle.net/11575/13275
Appare nelle tipologie:	1.1 Articolo in rivista

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