This is an "Opinion Article" addressing a number of critical "knowledge-deficient areas" regarding "cetacean host-pathogen interaction(s). These “knowledge-deficient areas” may be identified as follows: (1) characterization of the cell receptor(s) allowing infection; (2) interaction(s) and effects of chemical pollutants on the expression levels of the aforementioned cell receptors; (3) pathogenetic evolution of the concerned infections in T helper 1 (Th1)-dominant versus (vs.) Th2-dominant cetacean individuals; (4) effects of pregnancy-associated immune status on the infectious potential of the herein dealt pathogens; (5) usefulness of cetaceans and their pathogens as models for human disease.
Cetacean host-pathogen interaction(s): Critical knowledge gaps
Di Guardo
Writing – Original Draft Preparation
;
2018-01-01
Abstract
This is an "Opinion Article" addressing a number of critical "knowledge-deficient areas" regarding "cetacean host-pathogen interaction(s). These “knowledge-deficient areas” may be identified as follows: (1) characterization of the cell receptor(s) allowing infection; (2) interaction(s) and effects of chemical pollutants on the expression levels of the aforementioned cell receptors; (3) pathogenetic evolution of the concerned infections in T helper 1 (Th1)-dominant versus (vs.) Th2-dominant cetacean individuals; (4) effects of pregnancy-associated immune status on the infectious potential of the herein dealt pathogens; (5) usefulness of cetaceans and their pathogens as models for human disease.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
