Laparoscopy is a minimally invasive surgical technique; compared to laparotomy, it has several advantages such as less tissue exposure, reduced post-surgical pain, infection rate, and hospitalization time. Antibiotic therapy was found to be a predisposing factor to the development of antimicrobial resistance. The aim of the present study was to evaluate the incidence of SSI in dogs undergoing antibiotic free laparoscopic ovariectomies. The study was approved by the Ethics Committee of the University of Teramo (Prot. N. 23865, 30/09/21). Dogs presented to the Small Animals Teaching Hospital of the University of Teramo for elective two-port laparoscopic neutering were included. Patients were prepared with an aseptic technique and randomly divided into two groups. Group A received a 22mg/kg dose of Cefazolin intravenously 30 minutes before skin incision. Group B did not receive prophylactic antibiotics. Data collection included timing and dosage of antimicrobial administration, duration of surgery, and signs of SSI. Owners were informed about surgical wound management. Fifteen and thirty days after the surgery, the surgical wounds were assessed either in the clinic or through a phone interview with the owners. Dehiscence, fistula formation, purulent discharge, pain and/or excessive swelling were recorded, and cultural swab was performed if indicated. Data from two groups were presented as percentages and compared with Fisher’s exact test, with significance set at p ≤ 0.01. The overall SSI rate was 0/47 (0%) in the group A and 1/58 (1.72%) in the group B (p=1). One dog from group B developed swelling of surgical wounds 5 days after surgery. Culture was positive for E. coli. In accordance with antibiogram, amoxicillin-clavulanic acid was administered for 5 days and clinical signs resolved. Antibiotic prophylaxis during elective laparoscopic surgery appears avoidable, as there is no significant difference in SSI rates between dogs that received it and those that did not.
Assessment of Antibiotic Prophylaxis in Preventing Surgical Site Infections During Laparoscopic Ovariectomy in Dogs / Bianchi, Amanda. - (2026).
Assessment of Antibiotic Prophylaxis in Preventing Surgical Site Infections During Laparoscopic Ovariectomy in Dogs
Bianchi, Amanda
2026-01-01
Abstract
Laparoscopy is a minimally invasive surgical technique; compared to laparotomy, it has several advantages such as less tissue exposure, reduced post-surgical pain, infection rate, and hospitalization time. Antibiotic therapy was found to be a predisposing factor to the development of antimicrobial resistance. The aim of the present study was to evaluate the incidence of SSI in dogs undergoing antibiotic free laparoscopic ovariectomies. The study was approved by the Ethics Committee of the University of Teramo (Prot. N. 23865, 30/09/21). Dogs presented to the Small Animals Teaching Hospital of the University of Teramo for elective two-port laparoscopic neutering were included. Patients were prepared with an aseptic technique and randomly divided into two groups. Group A received a 22mg/kg dose of Cefazolin intravenously 30 minutes before skin incision. Group B did not receive prophylactic antibiotics. Data collection included timing and dosage of antimicrobial administration, duration of surgery, and signs of SSI. Owners were informed about surgical wound management. Fifteen and thirty days after the surgery, the surgical wounds were assessed either in the clinic or through a phone interview with the owners. Dehiscence, fistula formation, purulent discharge, pain and/or excessive swelling were recorded, and cultural swab was performed if indicated. Data from two groups were presented as percentages and compared with Fisher’s exact test, with significance set at p ≤ 0.01. The overall SSI rate was 0/47 (0%) in the group A and 1/58 (1.72%) in the group B (p=1). One dog from group B developed swelling of surgical wounds 5 days after surgery. Culture was positive for E. coli. In accordance with antibiogram, amoxicillin-clavulanic acid was administered for 5 days and clinical signs resolved. Antibiotic prophylaxis during elective laparoscopic surgery appears avoidable, as there is no significant difference in SSI rates between dogs that received it and those that did not.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
