Newest approach for micro- extraction from complex matrix

Until Green Chemistry, Green Analytical Chemistry and Green Sample Preparation were born, scientists focused their research on minimizing waste, reducing sample treatment, volume and solvent used. For this reason, in 2014 Kabir and Furton patented a new micro-extraction method, called Fabric Phase Sorptive Extraction (FPSE). This approach permits to avoid significantly sample treatment and the FPSE could directly put into the sample and analytes are adsorbed on the phase. In multi- analytes methods and due to chemistry of FPSE, sometimes the extraction is not the best for each compound. Based on this, Kabir and colleagues patented in 2024 a device which permits to extract simultaneously different analytes using more FPSE, by leveraging various surface chemistry of the sol- gel. The device has permitted to improve extraction yield of many compounds with different chemical characteristics in complex matrix, as plasma, blood, urine, and saliva could be. The device allows the ease extraction in biological and environmental matrices, the configuration permits to use a magnetic stirrer, increasing permeability of FPSE. Its size and configuration make it suitable for small volume. The configuration permits to add up to six different surface chemistry FPSE, in this way recovery will be maximized. The device has shown good results demonstrating applicability in many fields.