Lumpy skin disease (LSD) is caused by a Capripoxvirus (Poxviridae family), and affects primarily cattle. LSD is endemic in different African and Asian countries, and is also present in Europe, causing huge economic losses. Vaccination is one of the actions to prevent and limit the spread of the disease. Commercial vaccines available are live attenuated but their use is considered unsafe in non-endemic countries for the possibility of having adverse effects, such as reduced milk production. The aim of our study was the evaluation of the vaccine immunogenicity and its effects in dairy cows, concerning the quantity and quality of produced milk. The safety of the vaccine was previously tested in cattle, and was confirmed with this work in dairy cows. Moreover, qualitative and quantitative properties of the milk produced by vaccinated cows showed no differences when compared to the experimental control group, demonstrating the properties of vaccine not only in cattle, but also in dairy cows.
Studio dell’immunogenicità ed effetti sulla lattazione di un vaccino inattivato per la Lumpy Skin Disease (LSD): risultati preliminari
Di Matteo I.;F. Profeta;Rossi E.;
2023-01-01
Abstract
Lumpy skin disease (LSD) is caused by a Capripoxvirus (Poxviridae family), and affects primarily cattle. LSD is endemic in different African and Asian countries, and is also present in Europe, causing huge economic losses. Vaccination is one of the actions to prevent and limit the spread of the disease. Commercial vaccines available are live attenuated but their use is considered unsafe in non-endemic countries for the possibility of having adverse effects, such as reduced milk production. The aim of our study was the evaluation of the vaccine immunogenicity and its effects in dairy cows, concerning the quantity and quality of produced milk. The safety of the vaccine was previously tested in cattle, and was confirmed with this work in dairy cows. Moreover, qualitative and quantitative properties of the milk produced by vaccinated cows showed no differences when compared to the experimental control group, demonstrating the properties of vaccine not only in cattle, but also in dairy cows.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
