This work evaluated the role of the enzyme 5-lipoxygenase (5-LOX) in the pathogenesis of morpho-functional damage during equine cyathostominosis, a major equine parasitic disease. 5-LOX expression and activity appear significantly increased in animals infected with cyathostomins resistant to anthelmintic drugs when compared to horses infected by susceptible isolates, thus suggesting a certain involvement of this enzyme in the infection.[...]
5-Lipohygenase (5-LOX) in equine cyathostominosis: biochemical investigations.
GIACOMINELLI STUFFLER, Roberto;DI CESARE, ANGELA;TRAVERSA, Donato;
2013-01-01
Abstract
This work evaluated the role of the enzyme 5-lipoxygenase (5-LOX) in the pathogenesis of morpho-functional damage during equine cyathostominosis, a major equine parasitic disease. 5-LOX expression and activity appear significantly increased in animals infected with cyathostomins resistant to anthelmintic drugs when compared to horses infected by susceptible isolates, thus suggesting a certain involvement of this enzyme in the infection.[...]File in questo prodotto:
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